| 持股明細(資料日期：2026/08/31) |
| 持股名稱 | 比例 |
| AMGEN INC | 8.45% |
| VERTEX PHARMACEUTICALS | 8.05% |
| GILEAD SCIENCES | 7.21% |
| REGENERON PHARMACEUTICALS | 5.72% |
| ARGENX SE ADR | 3.80% |
| MODERNA | 3.62% |
| NATERA | 3.12% |
| REVOLUTION MEDICINES | 2.78% |
| ILLUMINA INC | 2.29% |
| ALNYLAM PHARMACEUTICALS | 2.27% |
| BIOGEN | 2.25% |
| BEONE MEDICINES AG | 2.03% |
| INSMED | 1.85% |
| INCYTE CORP | 1.73% |
| UNITED THERAPEUTICS | 1.49% |
| ROIVANT SCIENCES LTD | 1.27% |
| GENMAB SPONSORED ADR | 1.23% |
| ASCENDIS PHARMA | 1.15% |
| NEUROCRINE BIOSCIENCES | 1.08% |
| CHARLES RIVER LABORATORIES INTERNA | 0.97% |
| MEDPACE HOLDINGS | 0.97% |
| EXELIXIS INC | 0.94% |
| BRIDGEBIO PHARMA | 0.92% |
| HALOZYME THERAPEUTICS | 0.89% |
| BIOMARIN PHARMACEUTICAL | 0.88% |
| MADRIGAL PHARMACEUTICALS | 0.83% |
| BIO TECHNE | 0.80% |
| ARROWHEAD PHARMACEUTICALS | 0.77% |
| IONIS PHARMACEUTICALS | 0.69% |
| REPLIGEN | 0.68% |
| CYTOKINETICS | 0.67% |
| KRYSTAL BIOTECH | 0.66% |
| BIONTECH SE ADR | 0.66% |
| PRAXIS PRECISION MEDICINES | 0.65% |
| PROTAGONIST THERAPEUTICS | 0.64% |
| VAXCYTE | 0.61% |
| AXSOME THERAPEUTICS | 0.61% |
| KYMERA THERAPEUTICS | 0.60% |
| CRINETICS PHARMACEUTICALS | 0.59% |
| TWIST BIOSCIENCE | 0.59% |
| APOGEE THERAPEUTICS | 0.55% |
| ALKERMES | 0.54% |
| ABIVAX AMERICAN DEPOSITARY SHARES | 0.51% |
| 10X GENOMICS CLASS A | 0.50% |
| RHYTHM PHARMACEUTICALS | 0.50% |
| SPYRE THERAPEUTICS INC | 0.49% |
| TEMPUS AI CLASS A | 0.47% |
| BRUKER | 0.46% |
| TRAVERE THERAPEUTICS | 0.42% |
| XENON PHARMACEUTICALS | 0.39% |
| SCHOLAR ROCK HOLDING | 0.39% |
| PTC THERAPEUTICS | 0.39% |
| CRISPR THERAPEUTICS AG | 0.36% |
| DEFINIUM THERAPEUTICS INC | 0.36% |
| COGENT BIOSCIENCES | 0.36% |
| MIRUM PHARMACEUTICALS | 0.35% |
| ACADIA PHARMACEUTICALS | 0.35% |
| ORUKA THERAPEUTICS INC | 0.33% |
| CG ONCOLOGY | 0.31% |
| ERASCA | 0.31% |
| DYNE THERAPEUTICS | 0.27% |
| ADAPTIVE BIOTECHNOLOGIES | 0.27% |
| AMYLYX PHARMACEUTICALS | 0.25% |
| DENALI THERAPEUTICS | 0.25% |
| IDEAYA BIOSCIENCES | 0.24% |
| VERACYTE | 0.24% |
| IMMUNOVANT | 0.23% |
| EDGEWISE THERAPEUTICS | 0.23% |
| ENLIVEN THERAPEUTICS | 0.23% |
| GRAIL INC | 0.22% |
| IOVANCE BIOTHERAPEUTICS INC | 0.22% |
| LEGEND BIOTECH ADR REP | 0.22% |
| CARIS LIFE SCIENCES | 0.22% |
| UNIQURE | 0.22% |
| RELAY THERAPEUTICS | 0.21% |
| TARSUS PHARMACEUTICALS | 0.21% |
| IMMUNITYBIO INC | 0.21% |
| BEAM THERAPEUTICS | 0.20% |
| ARCUTIS BIOTHERAPEUTICS | 0.19% |
| ABCELLERA BIOLOGICS | 0.19% |
| STRUCTURE THERAPEUTICS ADR | 0.19% |
| TANGO THERAPEUTICS | 0.19% |
| NURIX THERAPEUTICS INC | 0.18% |
| ARCUS BIOSCIENCES | 0.17% |
| CAREDX | 0.17% |
| ULTRAGENYX PHARMACEUTICAL | 0.16% |
| ZAI LABORATORY ADR REPRESENTING LT | 0.16% |
| ZYMEWORKS | 0.15% |
| SAREPTA THERAPEUTICS | 0.15% |
| BIOCRYST PHARMACEUTICALS | 0.15% |
| ADMA BIOLOGICS | 0.15% |
| ATAIBECKLEY INC | 0.15% |
| DISC MEDICINE | 0.15% |
| KODIAK SCIENCES | 0.15% |
| BIOHAVEN | 0.14% |
| NEWAMSTERDAM PHARMA | 0.14% |
| VERA THERAPEUTICS CLASS A | 0.14% |
| VERICEL | 0.14% |
| XENCOR | 0.13% |
| NOVOCURE | 0.13% |
| SUMMIT THERAPEUTICS | 0.13% |
| AURINIA PHARMACEUTICALS | 0.13% |
| AGIOS PHARMACEUTICALS | 0.13% |
| ALUMIS | 0.13% |
| MBX BIOSCIENCES | 0.13% |
| GRIFOLS ADR REPRESENTING ONE NON-V | 0.12% |
| FORTREA HOLDINGS INC | 0.12% |
| INTELLIA THERAPEUTICS | 0.12% |
| NUVATION BIO CLASS A | 0.12% |
| UROGEN PHARMA | 0.12% |
| TREVI THERAPEUTICS | 0.11% |
| TAYSHA GENE THERAPIES | 0.11% |
| SYNDAX PHARMACEUTICALS | 0.11% |
| STOKE THERAPEUTICS | 0.11% |
| RECURSION PHARMACEUTICALS CLASS A | 0.11% |
| IMMUNOCORE HOLDINGS ADR PLC | 0.11% |
| MINERALYS THERAPEUTICS | 0.11% |
| ANAPTYSBIO | 0.11% |
| COMPASS PATHWAYS ADR PLC | 0.10% |
| INHIBRX BIOSCIENCES INC | 0.10% |
| NOVAVAX | 0.10% |
| RAPPORT THERAPEUTICS | 0.10% |
| VIR BIOTECHNOLOGY | 0.10% |
| REPLIMUNE GROUP | 0.09% |
| GH RESEARCH PLC | 0.09% |
| ALTO NEUROSCIENCE INC | 0.09% |
| ABSCI CORP | 0.09% |
| KURA ONCOLOGY | 0.08% |
| MANNKIND | 0.08% |
| MESOBLAST ADR REPRESENTING | 0.08% |
| LAKEFRONT BIOTHERAPEUTICS ADR NV | 0.08% |
| STEVANATO GROUP | 0.08% |
| PRECIGEN | 0.08% |
| TYRA BIOSCIENCES | 0.08% |
| ZENAS BIOPHARMA | 0.07% |
| PHARVARIS N V | 0.07% |
| PERSONALIS | 0.07% |
| SEPTERNA | 0.07% |
| JANUX THERAPEUTICS | 0.07% |
| MAZE THERAPEUTICS | 0.07% |
| MEIRAGTX HOLDINGS PLC | 0.07% |
| GERON | 0.07% |
| ARRIVENT BIOPHARMA | 0.07% |
| CULLINAN THERAPEUTICS | 0.07% |
| CASTLE BIOSCIENCES | 0.07% |
| CORVUS PHARMACEUTICALS | 0.06% |
| BICARA THERAPEUTICS INC | 0.06% |
| ANNEXON | 0.06% |
| ARBUTUS BIOPHARMA CORP | 0.06% |
| MONTE ROSA THERAPEUTICS | 0.06% |
| MARAVAI LIFESCIENCES HOLDINGS INC | 0.06% |
| RIGEL PHARMACEUTICALS | 0.06% |
| THERAVANCE BIOPHARMA | 0.06% |
| ORIC PHARMACEUTICALS | 0.06% |
| USD CASH | 0.06% |
| ZEVRA THERAPEUTICS INC | 0.05% |
| WAVE LIFE SCIENCES INC | 0.05% |
| OLEMA PHARMACEUTICALS | 0.05% |
| SOLID BIOSCIENCES INC | 0.05% |
| SANA BIOTECHNOLOGY | 0.05% |
| IRONWOOD PHARMA CLASS A | 0.05% |
| 4D MOLECULAR THERAPEUTICS INC | 0.05% |
| ACLARIS THERAPEUTICS | 0.05% |
| ALVOTECH SA | 0.05% |
| CANDEL THERAPEUTICS INC | 0.05% |
| CYTEK BIOSCIENCES | 0.04% |
| CYTOMX THERAPEUTICS | 0.04% |
| ALTIMMUNE INC | 0.04% |
| ALLOGENE THERAPEUTICS | 0.04% |
| ARVINAS | 0.04% |
| DESIGN THERAPEUTICS | 0.04% |
| SAGIMET BIOSCIENCES SERIES A | 0.04% |
| REGENXBIO | 0.04% |
| SAVARA | 0.04% |
| OMNIAB INC | 0.04% |
| OPKO HEALTH | 0.04% |
| NEUROGENE | 0.04% |
| PHATHOM PHARMACEUTICALS | 0.04% |
| PROTHENA PLC | 0.03% |
| PACIFIC BIOSCIENCES OF CALIFORNIA | 0.03% |
| SILENCE THERAPEUTICS ADR REPRESENT | 0.03% |
| ARS PHARMACEUTICALS | 0.03% |
| ROCKET PHARMACEUTICALS | 0.03% |
| EDITAS MEDICINE | 0.03% |
| ENANTA PHARMACEUTICALS INC | 0.03% |
| ARCTURUS THERAPEUTICS HOLDINGS INC | 0.03% |
| AURA BIOSCIENCES | 0.03% |
| AUTOLUS THERAPEUTICS ADR PLC | 0.03% |
| CONTINEUM THERAPEUTICS CLASS A | 0.03% |
| C4 THERAPEUTICS | 0.03% |
| BRIDGEBIO ONCOLOGY THERAPEUTICS IN | 0.03% |
| CABALETTA BIO | 0.03% |
| PERSPECTIVE THERAPEUTICS | 0.02% |
| BIOAGE LABS | 0.02% |
| ATEA PHARMACEUTICALS | 0.02% |
| ANAVEX LIFE SCIENCES CORP | 0.02% |
| FULGENT GENETICS | 0.02% |
| EMERGENT BIOSOLUTIONS | 0.02% |
| GINKGO BIOWORKS HOLDINGS CLASS A | 0.02% |
| FULCRUM THERAPEUTICS | 0.02% |
| IMMUNEERING CLASS A | 0.02% |
| KYVERNA THERAPEUTICS | 0.02% |
| STANDARD BIOTOOLS | 0.02% |
| MYRIAD GENETICS | 0.02% |
| LEXEO THERAPEUTICS | 0.02% |
| TECTONIC THERAPEUTIC | 0.02% |
| PRIME MEDICINE | 0.02% |
| VANDA PHARMACEUTICALS INC | 0.02% |
| UPSTREAM BIO | 0.02% |
| TENAYA THERAPEUTICS | 0.01% |
| ENTRADA THERAPEUTICS | 0.01% |
| VOYAGER THERAPEUTICS | 0.01% |
| BLK CSH FND TREASURY SL AGENCY | 0.01% |
| PEPGEN | 0.01% |
| PYXIS ONCOLOGY INC | 0.01% |
| QUANTUM SI INC CLASS A | 0.01% |
| QUANTERIX | 0.01% |
| NEUMORA THERAPEUTICS INC | 0.01% |
| NOVABRIDGE BIOSCIENCES ADR | 0.01% |
| ALPHA TEKNOVA | 0.01% |
| SIONNA THERAPEUTICS | 0.01% |
| LYELL IMMUNOPHARMA | 0.01% |
| LARIMAR THERAPEUTICS | 0.01% |
| LENZ THERAPEUTICS | 0.01% |
| LINEAGE CELL THERAPEUTICS INC | 0.01% |
| KEROS THERAPEUTICS | 0.01% |
| HUMACYTE INC | 0.01% |
| GOSSAMER BIO | 0.01% |
| CARIBOU BIOSCIENCES | 0.01% |
| FOGHORN THERAPEUTICS | 0.01% |
| ADC THERAPEUTICS SA | 0.01% |
| AARDVARK THERAPEUTICS | 0.01% |
| AC IMMUNE SA | 0.01% |
| BICYCLE THERAPEUTICS ADR PLC | 0.01% |
| BLACK DIAMOND THERAPEUTICS INC | 0.01% |
| CODEXIS | 0.01% |
| CELLECTIS ADR REPRESENTING SA | 0.01% |